Anti-Carbonylation: Carbonylation is a pathological step in the age-related
degradation of the body's proteins and Carnosine is the most
effective anti-carbonylation agent yet
discovered.
Antioxidant: Carnosine effectively quenches the most destructive of free
radicals, the hydroxyl radical, as well as super oxide,
singlet oxygen, and the peroxyl radical.
Cell Rejuvenation: Carnosine has the
unique and quite remarkable ability to actually rejuvenate
cells approaching senescence (the end of the life cycle of
dividing cells), restoring normal appearance and extending
their cellular life-span.
Wound
Healing: Carnosine has the amazing ability to rejuvenate
connective tissue cells and thus expedites wound
healing.
Brain Protection: Carnosine protects the microvasculature of the brain from
plaque formation that may lead to senility and Alzheimer's
disease.
Improved Calcium
Response: Carnosine enables the heart muscle to contract
more efficiently through enhancement of calcium response in
heart myocytes.
Cellular DNA
Protection: Carnosine protects cellular DNA from
oxidative damage that accumulates with age.
Skin Protection: Carnosine helps prevent
skin collagen cross-linking which leads to loss of elasticity,
wrinkles, macro-molecular disorganisation, and loss of extra
cellular matrix.
Cultures of senescent
cells cannot be mistaken for younger cells, which are uniform
in appearance and line up in parallel arrays. By contrast,
senescent cells exhibit a grainy appearance and take on odd
shapes and sizes. They lose the ability to organise themselves
in a regular pattern. These striking changes are called the
senescent phenotype. A dipeptide (chemical union of two amino
acids) called Carnosine has been shown to rejuvenate cells
displaying the senescent phenotype, quickly restoring the
juvenile phenotype (McFarland GA et al., 1999; McFarland GA et
al., 1994). Below are three photographs of human cells grown
in culture |